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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14d04c2e10a9f511094a910630a0a21ced7f7f3dcada730d9afc2a47452f048' 
  AND token = 'guAwOyOaCTsKVKvjMDqVD16u18+R1O6MdASgbl0By6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00116

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}