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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adad3a3de52e919439f50547d16a6401b217f14afeae3bfc95d3c2f2cda50c7' 
  AND token = 'OtL0qRZInzaoEvIsriTTSiNYFR1DtbAcwrUp7NNi4v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}