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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33e4d3cbe2212c2c94ab2698a08d3b1ac267605fd3d499433f7c3303ec9c10c' 
  AND token = 'v1dt49FcKi+Iv4txvlyzYlaPQ/6D9EkMAD7cYiOgxfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}