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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800b1005238d93eaf5c28d9d6690e345903cec424af08131398a1e2567605a0e' 
  AND token = '8kuUHXNAgSrUDQ7qdLgKAO1d4GgpLzivcB6LSjg9c90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}