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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21db9d9a640cc71cc0e8a8007e229e8902b1639c757d518d1b7999d61e00c94' 
  AND token = 'O5jJI28eD72uEwTSPEckX3PFxITJyMWPQ1w2rm7wjGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00126

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}