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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e26811b446aff55c014711ad1bf3506285dc33c265737b6740b86c0ed85472c' 
  AND token = 'cng2xUvPxLG5VjEYmdG7JmPFz7wlsCW7EM2TO3TZcMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}