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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bd153ec86907fb3fc1a423f099efe35c17a36de88ae00629b5b2e4bfc5acf5' 
  AND token = '2gci2Bgi2rbu1YFxWIRQPKKcFFFWUwQvaUwB7cnoqqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}