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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452ad1224e7b00248a8238f0b4100280d4f368fb859dc1b547e2592e91c9477e' 
  AND token = 'EiCaQfyWabB9x6zuXbAjJPzhRrWADS0aXY3TDgjRDQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}