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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49b98789e00dd93833f5e7bb20bafda0843950f221eba7e1df34ceb416052cc' 
  AND token = 'rX+1XMZFFkLXrnNrwX7I0vo+uUF1tTnrrNkdwFRpFmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}