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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e6f4b4179011714240d9d4d0c363d033a1551911eb0b7901d3f6c16bb44b916' 
  AND token = 'Htt/xujxqXH/b9bf3pdHyDOx3vCX2WPwXu5jtuW4HL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}