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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561b9caed432207d70f5cf460ba1a05412ea3abfb907dbd6aae21b4189f98035' 
  AND token = 'lcu7cVTDKqqOLsp/KOj3CXiGHtavlP5CNt1u4LYyuSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}