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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd39378acc1afe43b486fdf244720472c6b1f4c21e03ae17b1b05a45f12d0d7cd' 
  AND token = 'odIB0lzLPoiQuWfdIZVqQURTcASrko2sxbgHTHBk1b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}