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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f61ad32b36b1b601b44d8f4d5b98fc29f420bc7641a86370b229f7e2e6432b' 
  AND token = 'fFO4XxRfB6EPISIPOZh4JpAOVNF26osCdNXwlqpPWwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}