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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9abc988c2d576cfe0d62b8d80dff6bf470c1fbe4e61bb006909b1f688b1602' 
  AND token = 'FDwPFQQEyi7E5/27ZmpzYeLSgyKls+/1UtyLCT0Q3hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}