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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2580e358d847512ebb24734ba1b08a98a4f8e1262957b9f882ca230996669d9d' 
  AND token = 'xLh522aQyy9p7nX58kKLCzi8/5Ljo4aK7MDcyo8+KM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}