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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffd762e7f0c32961bdd8e6a40962c9654618251ef4a17f89c71716b3825a0d4' 
  AND token = 'DP2+0v3beDacYEagfyuuBDeqyXrxlkpzcoUYPk40eAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}