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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b2281925d97c6a6a36ff4cfeafe8a888e96cf5f5d7c9a097f2e698d767f521' 
  AND token = '1cG03KVOyLfnBeRtiN93QtPYGHlRfzOAwPl0fTYEfh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}