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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e96be5f23d15dbcf077e111d8606c46c4140c66a83d3402e6c4fcae5141a652' 
  AND token = 'jR19WanG/RNh9cq6kTOmcjM8TIrkPCdUZm3HaSz0cfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}