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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45b8d337cec23efa6f920009394b06a112ac0f4180c7ff629c4c0f608858f9c' 
  AND token = 'CpsC7kd/vh8hLHDEpcCajpdF2hQs8qkTk24j6jMDGZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}