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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644ac68d9709a9b558cba41fa3af3c0d59b11ad1d62ade4cf5c5751d4b04d0cb' 
  AND token = 'JHyqJooS1cULlFil+w4LZH9lCL4Kw4fDa/RdaXS5+rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}