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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9e9209e2d16fbf1cfe142079bd46a83898086b000cf4a9cb3d63bcbf4942b9' 
  AND token = '3OCOQmQzWiymm5voFXosxnbkXRl9LxSMaeQxkVRpI6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}