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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6250c59bc575891f6764c766d26890a588d79d8e9dc3be17b6d912e66803048b' 
  AND token = 'D1DPdbjYvprtJ5O2nHAdYDvQU+FUPGGBHlU2yM6Q3YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}