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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a21f060d20f1a6dee421fe172460611f77e47cbd5bf06ec9b6d973392e513a' 
  AND token = 'Nw4Uo6lSCPnVJ0jODXxTSOXs0ssZ8F9W8KP6yvuapCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}