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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8ab0330e45adbff24fb0167212a2e95c45965af3a1444bded1d3cc624abd75' 
  AND token = 'UBrF4VZqRhzWbpw2PRqldNV/IKhP1NBabnDi+9qNf04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}