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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8330c39eab419c27a0ac121ae06fe2ee45f8b9add41700d9db4d2ed20169213' 
  AND token = '+/GNSE2YudzJsVSJRR578mhg6dzo+57T0kI7a8w+r/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}