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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b46f4421606078d6ef093a3d94d23e676cec42cee94f8bcc44455a0efd1ab38' 
  AND token = 'Pv089WCl0VG6C75or1/A+nBPNE1BBplNPPNQBdU7sIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}