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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4ce658d5e568a87df35b1c4dff656f82d087d76a077e478f4cd1260e244603' 
  AND token = 'IoTW2yVZYbKIy5YcwrDNZnKIOxTMCZ4dz0f8R83da9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00126

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}