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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7b7af89da2b6b4ebfa9545008eff2399b92361de57d0596a069d0ca5b1f465' 
  AND token = '+1CX3fSIy/v0DfU5dlyDQ5abhNt3Ha8sHbTmaVxxydk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}