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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa2dcf1cfa452a2ac2c36ba88cc8287fbe028bf263b679142b5b6d64d278b5a' 
  AND token = 'swyIFsA+B+0w1JcSp1pSNlWgYT6CcZn62IUaN3IhFA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}