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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8a640d0e218216abf40dffa83bb730783742521a751383badaf92cd0e81029' 
  AND token = '3ghbUaDwn9gh9S5IKxmjMUec8L4Qmwmu29zELoBxbmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}