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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ff363282c1af6289f3c3b71edcbfb20e3100644ba9ebf4054c8e26241d4ecde' 
  AND token = 'sE7giz+OfQ7pardfbL89NnZ6/ErqPy0nQV294dfEOA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}