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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d1f15b094ca78d34d252df9bc2298e91fe7b8044427c9f5324678d59e4a1c8' 
  AND token = 'B8OFD3mQ9l0uFv0IVDuR8D87h8dh4pqXKcIaBQhudhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00132

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}