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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd519e51459e3dffea5217846e668d7d7793258dd5427e3e31619ea563e72f194' 
  AND token = 'B3Hxjpzj1yOuXeaqJLbvvkkbUiLJewsjqlcJ8kqWyac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}