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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7050577bfa4a3624408a2a38d8789a0ce4c4aa62c96681383fe6f00b46c1cb08' 
  AND token = 'M4p3GucNwi6tV+UvQN8JHc/a35WPOBOoKQOCFJ2X14I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}