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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43903ccac0dcf99644840ccee5917822e538b10f6c5921633a7e0df4f26573b6' 
  AND token = 'Y1HuvnV2X7+uP7874OFsbRSsWHFeN/tzRrA3qKxizwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}