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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bab83bd8d91809dd4d0ca45e54d3754911757df1b7a4c33b61b2cc0bdec3b3' 
  AND token = 'wOsJcLkxx/hKzUisqI2rFHRFRpLrHitW8oox6XufuJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}