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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1066cf20403632accf48e98157e9e6b9baced4f549d6419d6075e5d6275cf857' 
  AND token = 'buu8K/AqWCDvsCkyBWlRsX8SxOBYkE88f3dxxQ6i3Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}