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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf78ee5584100383bf84a50feaaa9d54fb29f5f61972b9090dc4fd20a3772a7' 
  AND token = 'e2mZN+Vh74UAvrPf/bkxTCXM8ZeoqoSMtoMRnI3ExBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}