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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef22c3c7eb705712ae03c2696b6e69642a5b305214c75fa98832987f2dbdcde' 
  AND token = 'WXMKp+IihY3QvLvHpQavzvuIkU97hr4oQG2nlLx8oWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}