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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72273429f87b037735b4be9c17d43cabd86b868e4a10d07c60b50a0d5c83812e' 
  AND token = 'lqTzldudWHzkvCaN4Eri4uJ2zw0rddJWgSnXt8E8Fkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}