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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7442f0631902bcce65cda04d2fa6a3349be110ba0b629d04ef4e76e109e821' 
  AND token = '/CDh/w+LobE7pbxG0P/lebwMgg8QQpACUK8qAQ8x+b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}