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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7b01dc50ee82c4de40a21a0eb29759b0263f665cae270f9171c0545d1350b7' 
  AND token = 'AmfP+f3O2Bgd/dllxnHECSE8ZgFp7jNN8f2/ro3BWtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}