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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c80218fe44d0b703dc1652c54c7f3c58a5d89d84955ec6671b658d1144d1eb1' 
  AND token = 'ZyOqDlDHhBqAs2iSa3Sxl+mtUjstHE01WFja6yWAsGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}