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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5eef68cd8829b22bc3e9f0d70549a2db5187b93dcb417cd573d9119b9af7e8' 
  AND token = 'sWXj+knsDyEtNiEG5zKH6lZuv0XnDGi7IRis2Y47oIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}