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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c6a9695cbbf76a3958f0bb7c058982f3bd305510ac5bed7c5777bb16cb600c' 
  AND token = 'kXMCc5kQOmZtfm+cz6VwjeTN5r9BowQ6E4kYxSj35Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}