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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9ef7150b5c8a6a8e67b7174493bb460640e7b3b4e03f102ff8633146983d0a' 
  AND token = 'htqX+qChxz5d0qnNP/+E0rg/iPD0FNElfjsWo22BQII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}