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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace4c1b54edeee43dd96c35c44045af288852fdcbc970f131e142649458f2b1f' 
  AND token = '1QsYc9kz2gzrFHa0/8u9HPISfjvDH2u4OLrx5LhPT0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}