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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5cd2b5948132ccf338a30a0d66b688ef4440c05ab572eba94a0dc9aa487441' 
  AND token = 'O4mkY/SNwJQJPbh1CS1oP+sYaKSwtWJ0XnPx4nL2fPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}