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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d18022b7b6c85fd2a25dbb028ae45ce2e056c1d51277c38e022449a8f07b25' 
  AND token = 'LBkW3+FZd1xH//KuRuJnsOR10TTNNDMM0PsywP9Vr2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}