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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e159eb7a82639a6b8e825051c55e7163500a1df16b5273250ae6b3a8cd3d9673' 
  AND token = 'GRR9kmkrWenAnFelhIClfiaj3iuP+Z+JM+gFnGVYd2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}